Kwabena Owusu has been handed a starting role by Kwesi Appiah with Kwadwo Asamoah benched as Ghana face on Guinea-Bissau today at 4:00 pm.
Also, Genk defender Joseph Aidoo will be making his AFCON debut as he will be partnering John Boye following the latter's return from suspension.
The duo are taking the place of the Kassim Nuhu and Jonathan Mensah who featured as Cameroon.
Kassim has been suspended for the game following accumulation of yellow cards while Jonathan Mensah is not fit to start.
Below is Ghana’s line up against the Wild Dogs of Guinea-Bissau
(GK) Richard Ofori
(C) Andre Ayew