Arsenal chiefs will have an extensive conversation with the players after images emerged allegedly showing four members of the first team inhaling nitrous oxide.
CCTV footage obtained by the Sun captured Alexandre Lacazette, Matteo Guendouzi, Mesut Ozil and Pierre-Emerick Aubameyang all inhaling from balloons allegedly containing the substance.
It was confirmed by an Arsenal spokesperson who told the BBC that players would be "spoken to and reminded of their responsibilities".
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While it is not illegal to possess the drug, it is illegal to give away or sell.