A cartoon cat, sick of the annoying mouse living in his home, devises a plot to take him out with a trap loaded with cheese. The mouse, wise to his plan, safely removes the snack and saunters away with a full belly.
You can probably guess what happens next. The story ends as it almost always does: with the cat yelling out in pain as yet another plot backfires.
The plot may be familiar, but the story behind it may not be. From Academy Award wins to secret production behind the Cold War's Iron Curtain - this is how Tom and Jerry, who turn 80 this week, became one of the world's best known double-acts.
The duo was dreamt up from a place of desperation. MGM's animation department, where creators Bill Hanna and Joe Barbera worked, had struggled to emulate the success of other studios who had hit characters like Porky Pig and Mickey Mouse.
Out of boredom, the animators, both aged under 30, began thinking up their own ideas. Barbera said he loved the simple concept of a cat and mouse cartoon, with conflict and chase, even though it had been done countless times before.
Puss gets the Boot was the first they released, in 1940. The debut was a hit and won the studio an Oscar nomination for best animated short. Despite their work, the animators were not credited.
Managers initially told them not to put all their eggs in one basket. A change of heart came only when a letter arrived from an influential industry figure in Texas asking when she would see another one of those "wonderful cat and mouse cartoons".
Jasper and Jinx, as they were first known, became Tom and Jerry.
According to Barbera there was no real discussion about the characters not speaking, but having grown up with silent films starring Charlie Chaplin, the creators knew they could be funny without dialogue. Music composed by Scott Bradley underscored the action and Tom's trademark human-like scream was voiced by Hanna himself.
For the best part of the next two decades, Hanna and Barbera oversaw the production of more than 100 of these shorts. Each took weeks to make and cost up to $50,000 to produce, so only a handful could be made every year.
These Tom and Jerrys are almost universally considered the best, with rich hand-drawn animation and detailed backdrops helping win them seven Academy Awards and cameos in Hollywood feature films.
"I'll bet when you watched them as a child, or even if you look at them right now, you would be hard-pressed to know when they were made," says Jerry Beck, a cartoon historian who has worked in roles across the industry.
"There's something about animation. It's evergreen, it doesn't fade," he says. "A drawing is a drawing, it's like when you go see paintings. Yes, we know they're from the 1800s or 1700s - it doesn't matter and it still speaks to you today."
"That's the thing with these cartoons. What we've learned in time is that they really are great art. They're not disposable throwaway entertainment."
When producer Fred Quimby retired in the mid-1950s, Hanna and Barbera took over MGM's cartoon department just as budget cuts closed in. Studio bosses, threatened by the growing popularity of television, realised they could make almost as much money by re-issuing the old shorts as they could by making new ones.
When their department was closed down in 1957, Hanna and Barbera set up their own production company.
But only a few years later, MGM decided to revive Tom and Jerry without its original creators. In 1961 they outsourced to a studio in Prague to save on costs. Chicago-born animator Gene Deitch was tasked with heading the remake, but struggled with a tight budget and staff with no knowledge of the original.
His studio also secretly made episodes of other cartoons, including Popeye. Czech names were Americanised on the credits to stop viewers associating the shows with Communism.